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Predictive value of single nucleotide polymorphisms in XRCC1 for radiation-induced normal tissue toxicity

PURPOSE: X-Ray Repair Cross Complementing 1 (XRCC1) functioning in the base excision repair pathway plays an important role in the repair of DNA single-strand breaks caused by ionizing radiation. The relationship between XRCC1 polymorphisms and the risk of radiation-induced side effects on normal ti...

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Detalles Bibliográficos
Autores principales: Zhao, Jing, Zhi, Zheng, Zhang, Ming, Li, Qingxia, Li, Jing, Wang, Xiao, Ma, Chunling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039069/
https://www.ncbi.nlm.nih.gov/pubmed/30013370
http://dx.doi.org/10.2147/OTT.S156175