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Kinetics of HIV-1 capsid uncoating revealed by single-molecule analysis

Uncoating of the metastable HIV-1 capsid is a tightly regulated disassembly process required for release of the viral cDNA prior to nuclear import. To understand the intrinsic capsid disassembly pathway and how it can be modulated, we have developed a single-particle fluorescence microscopy method t...

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Detalles Bibliográficos
Autores principales: Márquez, Chantal L, Lau, Derrick, Walsh, James, Shah, Vaibhav, McGuinness, Conall, Wong, Andrew, Aggarwal, Anupriya, Parker, Michael W, Jacques, David A, Turville, Stuart, Böcking, Till
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039174/
https://www.ncbi.nlm.nih.gov/pubmed/29877795
http://dx.doi.org/10.7554/eLife.34772