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Variations in HLA-B cell surface expression, half-life and extracellular antigen receptivity
The highly polymorphic human leukocyte antigen (HLA) class I molecules present peptide antigens to CD8(+) T cells, inducing immunity against infections and cancers. Quality control mediated by peptide loading complex (PLC) components is expected to ensure the cell surface expression of stable peptid...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039183/ https://www.ncbi.nlm.nih.gov/pubmed/29989547 http://dx.doi.org/10.7554/eLife.34961 |