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Variations in HLA-B cell surface expression, half-life and extracellular antigen receptivity

The highly polymorphic human leukocyte antigen (HLA) class I molecules present peptide antigens to CD8(+) T cells, inducing immunity against infections and cancers. Quality control mediated by peptide loading complex (PLC) components is expected to ensure the cell surface expression of stable peptid...

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Detalles Bibliográficos
Autores principales:	Yarzabek, Brogan, Zaitouna, Anita J, Olson, Eli, Silva, Gayathri N, Geng, Jie, Geretz, Aviva, Thomas, Rasmi, Krishnakumar, Sujatha, Ramon, Daniel S, Raghavan, Malini
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2018
Materias:	Immunology and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039183/ https://www.ncbi.nlm.nih.gov/pubmed/29989547 http://dx.doi.org/10.7554/eLife.34961

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