Pharmacokinetics of RP5063 Following Single Doses to Normal Healthy Volunteers and Multiple Doses Over 10 Days to Stable Schizophrenic Patients

RP5063, a multimodal dopamine (D)–serotonin (5‐HT) stabilizer, possesses high affinity for D(2/3/4) and 5‐HT(1A/2A/2B/2C/6/7) receptors and moderate affinity for the serotonin transporter. Two phase I studies characterized the pharmacokinetics of a single dose (10 and 15 mg fasting, 15 mg fed/fastin...

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Detalles Bibliográficos
Autores principales: Cantillon, Marc, Ings, Robert, Bhat, Laxminarayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039205/
https://www.ncbi.nlm.nih.gov/pubmed/29119704
http://dx.doi.org/10.1111/cts.12518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039205/
https://www.ncbi.nlm.nih.gov/pubmed/29119704
http://dx.doi.org/10.1111/cts.12518

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