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Inactivating hepatic follistatin alleviates hyperglycemia

Unsuppressed hepatic glucose production (HGP) contributes significantly to glucose intolerance and diabetes, which can be modeled by genetic inactivation of hepatic insulin receptor substrate (Irs) 1 and Irs2 (LDKO-mice). We previously showed that glucose intolerance in LDKO-mice is resolved by hepa...

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Detalles Bibliográficos
Autores principales: Tao, Rongya, Wang, Caixia, Stöhr, Oliver, Qiu, Wei, Hu, Yue, Miao, Ji, Dong, X. Charlie, Leng, Sining, Stefater, Margaret, Stylopoulos, Nicholas, Lin, Lin, Copps, Kyle D., White, Morris F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039237/
https://www.ncbi.nlm.nih.gov/pubmed/29867232
http://dx.doi.org/10.1038/s41591-018-0048-0