High-throughput Cos-Seq screen with intracellular Leishmania infantum for the discovery of novel drug-resistance mechanisms

Increasing drug resistance towards first line antimony-derived compounds has forced the introduction of novel therapies in leishmaniasis endemic areas including amphotericin B and miltefosine. However, their use is threatened by the emergence and spread of drug-resistant strains. In order to discove...

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Detalles Bibliográficos
Autores principales: Fernandez-Prada, Christopher, Sharma, Mansi, Plourde, Marie, Bresson, Eva, Roy, Gaétan, Leprohon, Philippe, Ouellette, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039308/
https://www.ncbi.nlm.nih.gov/pubmed/29602064
http://dx.doi.org/10.1016/j.ijpddr.2018.03.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039308/
https://www.ncbi.nlm.nih.gov/pubmed/29602064
http://dx.doi.org/10.1016/j.ijpddr.2018.03.004

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