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Activity of bromodomain protein inhibitors/binders against asexual-stage Plasmodium falciparum parasites

Bromodomain-containing proteins (BDPs) are involved in the regulation of eukaryotic gene expression. Compounds that bind and/or inhibit BDPs are of interest as tools to better understand epigenetic regulation, and as possible drug leads for different diseases, including malaria. In this study, we as...

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Detalles Bibliográficos
Autores principales: Chua, Ming Jang, Robaa, Dina, Skinner-Adams, Tina S., Sippl, Wolfgang, Andrews, Katherine T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039313/
https://www.ncbi.nlm.nih.gov/pubmed/29631126
http://dx.doi.org/10.1016/j.ijpddr.2018.03.001