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Activity of bromodomain protein inhibitors/binders against asexual-stage Plasmodium falciparum parasites
Bromodomain-containing proteins (BDPs) are involved in the regulation of eukaryotic gene expression. Compounds that bind and/or inhibit BDPs are of interest as tools to better understand epigenetic regulation, and as possible drug leads for different diseases, including malaria. In this study, we as...
Autores principales: | Chua, Ming Jang, Robaa, Dina, Skinner-Adams, Tina S., Sippl, Wolfgang, Andrews, Katherine T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039313/ https://www.ncbi.nlm.nih.gov/pubmed/29631126 http://dx.doi.org/10.1016/j.ijpddr.2018.03.001 |
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