Cargando…

Weibel-Palade Body Localized Syntaxin-3 Modulates Von Willebrand Factor Secretion From Endothelial Cells

OBJECTIVE—: Endothelial cells store VWF (von Willebrand factor) in rod-shaped secretory organelles, called Weibel-Palade bodies (WPBs). WPB exocytosis is coordinated by a complex network of Rab GTPases, Rab effectors, and SNARE (soluble NSF attachment protein receptor) proteins. We have previously i...

Descripción completa

Detalles Bibliográficos
Autores principales: Schillemans, Maaike, Karampini, Ellie, van den Eshof, Bart L., Gangaev, Anastasia, Hofman, Menno, van Breevoort, Dorothee, Meems, Henriët, Janssen, Hans, Mulder, Aat A., Jost, Carolina R., Escher, Johanna C., Adam, Rüdiger, Carter, Tom, Koster, Abraham J., van den Biggelaar, Maartje, Voorberg, Jan, Bierings, Ruben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039413/
https://www.ncbi.nlm.nih.gov/pubmed/29880488
http://dx.doi.org/10.1161/ATVBAHA.117.310701