Liver-specific deletion of Eva1a/Tmem166 aggravates acute liver injury by impairing autophagy

Acute liver failure (ALF) is an inflammation-mediated hepatocellular injury process associated with cellular autophagy. However, the mechanism by which autophagy regulates ALF remains undefined. Herein, we demonstrated that Eva1a (eva-1 homolog A)/Tmem166 (transmembrane protein 166), an autophagy-re...

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Detalles Bibliográficos
Autores principales: Lin, Xin, Cui, Ming, Xu, Dong, Hong, Dubeiqi, Xia, Yan, Xu, Chentong, Li, Riyong, Zhang, Xuan, Lou, Yaxin, He, Qihua, Lv, Ping, Chen, Yingyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039435/
https://www.ncbi.nlm.nih.gov/pubmed/29991758
http://dx.doi.org/10.1038/s41419-018-0800-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039435/
https://www.ncbi.nlm.nih.gov/pubmed/29991758
http://dx.doi.org/10.1038/s41419-018-0800-x

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