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Antibody targeting of a specific region of Pfs47 blocks Plasmodium falciparum malaria transmission

Transmission-blocking vaccines are based on eliciting antibody responses in the vertebrate host that disrupt parasite development in the mosquito vector and prevent malaria transmission. The surface protein Pfs47 is present in Plasmodium falciparum gametocytes and female gametes. The potential of Pf...

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Detalles Bibliográficos
Autores principales: Canepa, Gaspar E., Molina-Cruz, Alvaro, Yenkoidiok-Douti, Lampouguin, Calvo, Eric, Williams, Adeline E., Burkhardt, Martin, Peng, Fangni, Narum, David, Boulanger, Martin J., Valenzuela, Jesus G., Barillas-Mury, Carolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039440/
https://www.ncbi.nlm.nih.gov/pubmed/30002917
http://dx.doi.org/10.1038/s41541-018-0065-5