Cargando…
Antibody targeting of a specific region of Pfs47 blocks Plasmodium falciparum malaria transmission
Transmission-blocking vaccines are based on eliciting antibody responses in the vertebrate host that disrupt parasite development in the mosquito vector and prevent malaria transmission. The surface protein Pfs47 is present in Plasmodium falciparum gametocytes and female gametes. The potential of Pf...
Autores principales: | Canepa, Gaspar E., Molina-Cruz, Alvaro, Yenkoidiok-Douti, Lampouguin, Calvo, Eric, Williams, Adeline E., Burkhardt, Martin, Peng, Fangni, Narum, David, Boulanger, Martin J., Valenzuela, Jesus G., Barillas-Mury, Carolina |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039440/ https://www.ncbi.nlm.nih.gov/pubmed/30002917 http://dx.doi.org/10.1038/s41541-018-0065-5 |
Ejemplares similares
-
Engineering a Virus-Like Particle as an Antigenic Platform for a Pfs47-Targeted Malaria Transmission-Blocking Vaccine
por: Yenkoidiok-Douti, Lampouguin, et al.
Publicado: (2019) -
In vivo Characterization of Plasmodium berghei P47 (Pbs47) as a Malaria Transmission-Blocking Vaccine Target
por: Yenkoidiok-Douti, Lampouguin, et al.
Publicado: (2020) -
Molecular Analysis of Pfs47-Mediated Plasmodium Evasion of Mosquito Immunity
por: Canepa, Gaspar E., et al.
Publicado: (2016) -
Role of Pfs47 in the dispersal of ancestral Plasmodium falciparum malaria through adaptation to different anopheline vectors
por: Molina-Cruz, Alvaro, et al.
Publicado: (2023) -
The remarkable journey of adaptation of the Plasmodium
falciparum malaria parasite to New World anopheline
mosquitoes
por: Molina-Cruz, Alvaro, et al.
Publicado: (2014)