A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA

The high rate of antigenic drift in seasonal influenza viruses necessitates frequent changes in vaccine composition. Recent seasonal H3 vaccines do not protect against swine-origin H3N2 variant (H3N2v) strains that recently have caused severe human infections. Here, we report a human V(H)1-69 gene-e...

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Detalles Bibliográficos
Autores principales: Bangaru, Sandhya, Zhang, Heng, Gilchuk, Iuliia M., Voss, Thomas G., Irving, Ryan P., Gilchuk, Pavlo, Matta, Pranathi, Zhu, Xueyong, Lang, Shanshan, Nieusma, Travis, Richt, Juergen A., Albrecht, Randy A., Vanderven, Hillary A., Bombardi, Robin, Kent, Stephen J., Ward, Andrew B., Wilson, Ian A., Crowe, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039445/
https://www.ncbi.nlm.nih.gov/pubmed/29991715
http://dx.doi.org/10.1038/s41467-018-04704-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039445/
https://www.ncbi.nlm.nih.gov/pubmed/29991715
http://dx.doi.org/10.1038/s41467-018-04704-9

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