Patterns of genomic evolution in advanced melanoma

Genomic alterations occurring during melanoma progression and the resulting genomic heterogeneity between metastatic deposits remain incompletely understood. Analyzing 86 metastatic melanoma deposits from 53 patients with whole-exome sequencing (WES), we show a low branch to trunk mutation ratio and...

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Detalles Bibliográficos
Autores principales: Birkeland, E., Zhang, S., Poduval, D., Geisler, J., Nakken, S., Vodak, D., Meza-Zepeda, L. A., Hovig, E., Myklebost, O., Knappskog, S., Lønning, P. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039447/
https://www.ncbi.nlm.nih.gov/pubmed/29991680
http://dx.doi.org/10.1038/s41467-018-05063-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039447/
https://www.ncbi.nlm.nih.gov/pubmed/29991680
http://dx.doi.org/10.1038/s41467-018-05063-1

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