Cargando…

Oncogenic addiction to high 26S proteasome level

Proteasomes are large intracellular complexes responsible for the degradation of cellular proteins. The altered protein homeostasis of cancer cells results in increased dependency on proteasome function. The cellular proteasome composition comprises the 20S catalytic complex that is frequently cappe...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsvetkov, Peter, Adler, Julia, Myers, Nadav, Biran, Assaf, Reuven, Nina, Shaul, Yosef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039477/
https://www.ncbi.nlm.nih.gov/pubmed/29991718
http://dx.doi.org/10.1038/s41419-018-0806-4