The autophagic degradation of Cav-1 contributes to PA-induced apoptosis and inflammation of astrocytes

The accumulation of palmitic acid (PA), implicated in obesity, can induce apoptotic cell death and inflammation of astrocytes. Caveolin-1 (Cav-1), an essential protein for astrocytes survival, can be degraded by autophagy, which is a double-edge sword that can either promote cell survival or cell de...

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Detalles Bibliográficos
Autores principales: Chen, Zi, Nie, Sheng-Dan, Qu, Min-Li, Zhou, Di, Wu, Liang-Yan, Shi, Xia-Jie, Ma, Ling-Ran, Li, Xin, Zhou, Shan-Lei, Wang, Shan, Wu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039485/
https://www.ncbi.nlm.nih.gov/pubmed/29991726
http://dx.doi.org/10.1038/s41419-018-0795-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039485/
https://www.ncbi.nlm.nih.gov/pubmed/29991726
http://dx.doi.org/10.1038/s41419-018-0795-3

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