miR-34a exerts as a key regulator in the dedifferentiation of osteosarcoma via PAI-1–Sox2 axis

Osteosarcoma (OS) is a malignant bone cancer with severe chromosomal abnormalities and genetic aberrations. Our previous work reported the dedifferentiation of OS, which is related to poor prognosis. However, the molecular mechanism that regulates OS dedifferentiation is still a subject of explorati...

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Detalles Bibliográficos
Autores principales: Zhang, Yu, Pan, Yubin, Xie, Chunyuan, Zhang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039486/
https://www.ncbi.nlm.nih.gov/pubmed/29991717
http://dx.doi.org/10.1038/s41419-018-0778-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039486/
https://www.ncbi.nlm.nih.gov/pubmed/29991717
http://dx.doi.org/10.1038/s41419-018-0778-4

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