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CUEDC2, a novel interacting partner of the SOCS1 protein, plays important roles in the leukaemogenesis of acute myeloid leukaemia

Downregulation of suppressor of cytokine signalling-1 (SOCS1) is one of the vital reasons for JAK1-STAT3 pathway activation in acute myeloid leukaemia (AML). CUE domain-containing 2 (CUEDC2) was a novel interacting partner of SOCS1 and a positive correlation between the expression of CUEDC2 and SOCS...

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Detalles Bibliográficos
Autores principales: Wu, Qing-Yun, Zhu, Yuan-Yuan, Liu, Yang, Wei, Fang, Tong, Yu-Xue, Cao, Jiang, Zhou, Ping, Niu, Ming-Shan, Li, Zhen-Yu, Zeng, Ling-Yu, Li, Feng, Xu, Kai-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039501/
https://www.ncbi.nlm.nih.gov/pubmed/29991678
http://dx.doi.org/10.1038/s41419-018-0812-6