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CCL5-deficiency enhances intratumoral infiltration of CD8(+) T cells in colorectal cancer

Colorectal cancer (CRC) is the third most common solid tumor in the world and shows resistance to several immunotherapies, particularly immune checkpoint blockade which has therapeutic effects on many other types of cancer. Cytotoxic CD8(+) T cell has been considered as one of the main populations o...

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Detalles Bibliográficos
Autores principales: Zhang, Shengbo, Zhong, Ming, Wang, Chao, Xu, Yanjie, Gao, Wei-Qiang, Zhang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039518/
https://www.ncbi.nlm.nih.gov/pubmed/29991744
http://dx.doi.org/10.1038/s41419-018-0796-2