Proteomics Analysis of Monocyte-Derived Hepatocyte-Like Cells Identifies Integrin Beta 3 as a Specific Biomarker for Drug-Induced Liver Injury by Diclofenac

Idiosyncratic drug-induced liver injury (iDILI) is a major cause of acute liver failure resulting in liver transplantation or death. Prediction and diagnosis of iDILI remain a great challenge, as current models provide unsatisfying results in terms of sensitivity, specificity, and prognostic value....

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Detalles Bibliográficos
Autores principales: Dragoi, Diana, Benesic, Andreas, Pichler, Garwin, Kulak, Nils A., Bartsch, Harald S., Gerbes, Alexander L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039575/
https://www.ncbi.nlm.nih.gov/pubmed/30022949
http://dx.doi.org/10.3389/fphar.2018.00699

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039575/
https://www.ncbi.nlm.nih.gov/pubmed/30022949
http://dx.doi.org/10.3389/fphar.2018.00699

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