Antitumour, acute toxicity and molecular modeling studies of 4-(pyridin-4-yl)-6-(thiophen-2-yl) pyrimidin-2(1H)-one against Ehrlich ascites carcinoma and sarcoma-180

In an effort to discover an effective and selective antitumour agent, synthesis and anti-cancer potential of 4-(pyridin-4-yl)-6-(thiophen-2-yl) pyrimidin-2(1H)-one (SK-25), which has been reported earlier by us with significant cytotoxicity towards MiaPaCa-2 malignant cells, with an IC(50) value of...

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Detalles Bibliográficos
Autores principales: Kumar, Dinesh, Sharma, Pooja, Nepali, Kunal, Mahajan, Girish, Mintoo, Mubashir J., Singh, Amarinder, Singh, Gurpreet, Mondhe, Dilip M., Singh, Gurdarshan, Jain, Subheet K., Gupta, Girish K., Ntie-Kang, Fidele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039700/
https://www.ncbi.nlm.nih.gov/pubmed/30003157
http://dx.doi.org/10.1016/j.heliyon.2018.e00661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039700/
https://www.ncbi.nlm.nih.gov/pubmed/30003157
http://dx.doi.org/10.1016/j.heliyon.2018.e00661

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