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Visualizing Mitochondrial F(o)F(1)-ATP Synthase as the Target of the Immunomodulatory Drug Bz-423
Targeting the mitochondrial enzyme F(o)F(1)-ATP synthase and modulating its catalytic activities with small molecules is a promising new approach for treatment of autoimmune diseases. The immunomodulatory compound Bz-423 is such a drug that binds to subunit OSCP of the mitochondrial F(o)F(1)-ATP syn...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039829/ https://www.ncbi.nlm.nih.gov/pubmed/30022951 http://dx.doi.org/10.3389/fphys.2018.00803 |