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Accelerated placental aging in early onset preeclampsia pregnancies identified by DNA methylation

AIM: To determine whether dynamic DNA methylation changes in the human placenta can be used to predict gestational age. MATERIALS & METHODS: Publicly available placental DNA methylation data from 12 studies, together with our own dataset, using Illumina Infinium Human Methylation BeadChip arrays...

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Detalles Bibliográficos
Autores principales: Mayne, Benjamin T, Leemaqz, Shalem Y, Smith, Alicia K, Breen, James, Roberts, Claire T, Bianco-Miotto, Tina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040051/
https://www.ncbi.nlm.nih.gov/pubmed/27894195
http://dx.doi.org/10.2217/epi-2016-0103