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DSPP-MMP20 gene silencing downregulates cancer stem cell markers in human oral cancer cells

BACKGROUND: Recent findings indicate that dentin sialophosphoprotein (DSPP) and matrix metalloproteinase (MMP) 20 interact in oral squamous cell carcinoma (OSCC). The objective of this study was to determine the effects of DSPP/MMP20 gene silencing on oral cancer stem cell (OCSC) markers. METHODS: T...

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Detalles Bibliográficos
Autores principales: Nikitakis, Nikolaos G., Gkouveris, Ioannis, Aseervatham, Jaya, Barahona, Kelvin, Ogbureke, Kalu U. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040065/
https://www.ncbi.nlm.nih.gov/pubmed/30002682
http://dx.doi.org/10.1186/s11658-018-0096-y