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Apelin/APJ axis improves angiotensin II-induced endothelial cell senescence through AMPK/SIRT1 signaling pathway

INTRODUCTION: Previous studies have shown that endothelial cell senescence is involved in cardiovascular diseases such as cardiac fibrosis, atherosclerosis and heart failure. Accumulating evidence indicates that apelin exerts protective effects on ageing-related endothelial dysfunction. In this stud...

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Detalles Bibliográficos
Autores principales: Yang, Rongfeng, Fang, Wu, Liang, Jiawen, Lin, Chao, Wu, Shaoyun, Yan, Shaodi, Hu, Chengheng, Ke, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040122/
https://www.ncbi.nlm.nih.gov/pubmed/30002688
http://dx.doi.org/10.5114/aoms.2017.70340