The effect of CYP2C9*2, CYP2C9*3, and VKORC1-1639 G>A polymorphism in patients under warfarin therapy in city of Kermanshah

Polymorphism in the genes encoding CYP2C9 enzyme and VKORC1 reductase significantly influence warfarin dose requirement since patients with CYP2C9*2, CYP2C9*3 and VKORC1 mutant alleles require lower warfarin maintenance doses. Studies have reported the ethnic variations in the frequency of these gen...

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Detalles Bibliográficos
Autores principales: Hosseinkhani, Zohreh, Sadeghalvad, Mona, Norooznezhad, Fathemeh, Khodarahmi, Reza, Fazilati, Mohammad, Mahnam, Azadeh, Fattahi, Ali, Mansouri, Kamran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040167/
https://www.ncbi.nlm.nih.gov/pubmed/30065771
http://dx.doi.org/10.4103/1735-5362.235165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040167/
https://www.ncbi.nlm.nih.gov/pubmed/30065771
http://dx.doi.org/10.4103/1735-5362.235165

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