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The effect of CYP2C9*2, CYP2C9*3, and VKORC1-1639 G>A polymorphism in patients under warfarin therapy in city of Kermanshah
Polymorphism in the genes encoding CYP2C9 enzyme and VKORC1 reductase significantly influence warfarin dose requirement since patients with CYP2C9*2, CYP2C9*3 and VKORC1 mutant alleles require lower warfarin maintenance doses. Studies have reported the ethnic variations in the frequency of these gen...
Autores principales: | Hosseinkhani, Zohreh, Sadeghalvad, Mona, Norooznezhad, Fathemeh, Khodarahmi, Reza, Fazilati, Mohammad, Mahnam, Azadeh, Fattahi, Ali, Mansouri, Kamran |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040167/ https://www.ncbi.nlm.nih.gov/pubmed/30065771 http://dx.doi.org/10.4103/1735-5362.235165 |
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