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Retinal Basal Laminar Deposits in Complement fH/fP Mouse Model of Dense Deposit Disease
PURPOSE: Dense deposit disease (DDD) is caused by dysregulation of the alternative pathway of the complement cascade and characterized by electron-dense deposits in the kidney glomerular basement membrane (GBM) and drusen in Bruch's membrane (BrM). Complement factor H (fH) and factor properdin...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040236/ https://www.ncbi.nlm.nih.gov/pubmed/30025090 http://dx.doi.org/10.1167/iovs.18-24133 |