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Retinal Basal Laminar Deposits in Complement fH/fP Mouse Model of Dense Deposit Disease

PURPOSE: Dense deposit disease (DDD) is caused by dysregulation of the alternative pathway of the complement cascade and characterized by electron-dense deposits in the kidney glomerular basement membrane (GBM) and drusen in Bruch's membrane (BrM). Complement factor H (fH) and factor properdin...

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Detalles Bibliográficos
Autores principales:	Song, Delu, Mohammed, Imran, Bhuyan, Rupak, Miwa, Takashi, Williams, Allison Lesher, Gullipalli, Damodar, Sato, Sayaka, Song, Ying, Dunaief, Joshua L., Song, Wen-Chao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2018
Materias:	Retina
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040236/ https://www.ncbi.nlm.nih.gov/pubmed/30025090 http://dx.doi.org/10.1167/iovs.18-24133

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