Metformin Improves Epithelial-to-Mesenchymal Transition Induced by TGF-β1 in Renal Tubular Epithelial NRK-52E Cells via Inhibiting Egr-1

The early growth response- (Egr-) 1 has been found to play a key role in organ fibrosis. Metformin has been shown to be effective in attenuating renal tubular epithelial-to-mesenchymal transition (EMT), which is involved in renal fibrosis. However, it is unknown whether metformin improves EMT via in...

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Detalles Bibliográficos
Autores principales: Guan, Meiping, Li, Wenqi, Xu, Lingling, Zeng, Yanmei, Wang, Dan, Zheng, Zongji, Lyv, Fuping, Xue, Yaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040246/
https://www.ncbi.nlm.nih.gov/pubmed/30050950
http://dx.doi.org/10.1155/2018/1031367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040246/
https://www.ncbi.nlm.nih.gov/pubmed/30050950
http://dx.doi.org/10.1155/2018/1031367

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