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Metformin Improves Epithelial-to-Mesenchymal Transition Induced by TGF-β1 in Renal Tubular Epithelial NRK-52E Cells via Inhibiting Egr-1

The early growth response- (Egr-) 1 has been found to play a key role in organ fibrosis. Metformin has been shown to be effective in attenuating renal tubular epithelial-to-mesenchymal transition (EMT), which is involved in renal fibrosis. However, it is unknown whether metformin improves EMT via in...

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Detalles Bibliográficos
Autores principales:	Guan, Meiping, Li, Wenqi, Xu, Lingling, Zeng, Yanmei, Wang, Dan, Zheng, Zongji, Lyv, Fuping, Xue, Yaoming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040246/ https://www.ncbi.nlm.nih.gov/pubmed/30050950 http://dx.doi.org/10.1155/2018/1031367

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