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Simvastatin Improves the Jaw Bone Microstructural Defect Induced by High Cholesterol Diet in Rats by Regulating Autophagic Flux

OBJECTIVE: The objective of this study is to evaluate the effect of simvastatin on the jaw bone microstructural defect and autophagy in rats with high cholesterol diet (HCD). METHODS: Male Sprague-Dawley rats were fed a standard rodent chow (NC group) or a high cholesterol diet for 32 weeks and the...

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Detalles Bibliográficos
Autores principales: Zhou, Jianhua, Gao, Xiaoli, Huang, Shengyun, Ma, Li, Cui, Yanjun, Wang, Hengkun, Qiu, Jianzhong, Wang, Lili, Dong, Quanjiang, Chen, Zhenggang, Wang, Xuxia, Zhang, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040281/
https://www.ncbi.nlm.nih.gov/pubmed/30050930
http://dx.doi.org/10.1155/2018/4147932