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Using ROS as a Second Messenger, NADPH Oxidase 2 Mediates Macrophage Senescence via Interaction with NF-κB during Pseudomonas aeruginosa Infection

Pseudomonas aeruginosa (PA) is one of the most prevalent pathogens that cause nosocomial infection in critical patients. However, the mechanisms underlying macrophage growth status and functional changes during PA infection are yet unknown. In the present study, NADPH oxidase, gp91(phox) (NOX2) medi...

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Detalles Bibliográficos
Autores principales: Li, Hui, Luo, Yi-Feng, Wang, Yong-Sheng, Yang, Qing, Xiao, Yong-Long, Cai, Hou-Rong, Xie, Can-Mao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040290/
https://www.ncbi.nlm.nih.gov/pubmed/30050663
http://dx.doi.org/10.1155/2018/9741838