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Using ROS as a Second Messenger, NADPH Oxidase 2 Mediates Macrophage Senescence via Interaction with NF-κB during Pseudomonas aeruginosa Infection
Pseudomonas aeruginosa (PA) is one of the most prevalent pathogens that cause nosocomial infection in critical patients. However, the mechanisms underlying macrophage growth status and functional changes during PA infection are yet unknown. In the present study, NADPH oxidase, gp91(phox) (NOX2) medi...
Autores principales: | Li, Hui, Luo, Yi-Feng, Wang, Yong-Sheng, Yang, Qing, Xiao, Yong-Long, Cai, Hou-Rong, Xie, Can-Mao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040290/ https://www.ncbi.nlm.nih.gov/pubmed/30050663 http://dx.doi.org/10.1155/2018/9741838 |
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