Cargando…

Two critical positions in zinc finger domains are heavily mutated in three human cancer types

A major goal of cancer genomics is to identify somatic mutations that play a role in tumor initiation or progression. Somatic mutations within transcription factors are of particular interest, as gene expression dysregulation is widespread in cancers. The substantial gene expression variation eviden...

Descripción completa

Detalles Bibliográficos
Autores principales: Munro, Daniel, Ghersi, Dario, Singh, Mona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040777/
https://www.ncbi.nlm.nih.gov/pubmed/29953437
http://dx.doi.org/10.1371/journal.pcbi.1006290