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Two critical positions in zinc finger domains are heavily mutated in three human cancer types
A major goal of cancer genomics is to identify somatic mutations that play a role in tumor initiation or progression. Somatic mutations within transcription factors are of particular interest, as gene expression dysregulation is widespread in cancers. The substantial gene expression variation eviden...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040777/ https://www.ncbi.nlm.nih.gov/pubmed/29953437 http://dx.doi.org/10.1371/journal.pcbi.1006290 |