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Phosphorylation of human TRM9L integrates multiple stress-signaling pathways for tumor growth suppression

The human transfer RNA methyltransferase 9–like gene (TRM9L, also known as KIAA1456) encodes a negative regulator of tumor growth that is frequently silenced in many forms of cancer. While TRM9L can inhibit tumor cell growth in vivo, the molecular mechanisms underlying the tumor inhibition activity...

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Detalles Bibliográficos
Autores principales: Gu, Chen, Ramos, Jillian, Begley, Ulrike, Dedon, Peter C., Fu, Dragony, Begley, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040840/
https://www.ncbi.nlm.nih.gov/pubmed/30009260
http://dx.doi.org/10.1126/sciadv.aas9184