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Phosphorylation of human TRM9L integrates multiple stress-signaling pathways for tumor growth suppression
The human transfer RNA methyltransferase 9–like gene (TRM9L, also known as KIAA1456) encodes a negative regulator of tumor growth that is frequently silenced in many forms of cancer. While TRM9L can inhibit tumor cell growth in vivo, the molecular mechanisms underlying the tumor inhibition activity...
Autores principales: | Gu, Chen, Ramos, Jillian, Begley, Ulrike, Dedon, Peter C., Fu, Dragony, Begley, Thomas J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040840/ https://www.ncbi.nlm.nih.gov/pubmed/30009260 http://dx.doi.org/10.1126/sciadv.aas9184 |
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