Establishment of environmentally sensitive DNA methylation states in the very early human embryo

The molecular mechanisms responsible for the developmental origins of later disease are currently unknown. We previously demonstrated that women’s periconceptional nutrition predicts their offspring’s DNA methylation at metastable epialleles (MEs). We present a genome-wide screen yielding 687 MEs an...

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Detalles Bibliográficos
Autores principales: Kessler, Noah J., Waterland, Robert A., Prentice, Andrew M., Silver, Matt J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040841/
https://www.ncbi.nlm.nih.gov/pubmed/30009262
http://dx.doi.org/10.1126/sciadv.aat2624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040841/
https://www.ncbi.nlm.nih.gov/pubmed/30009262
http://dx.doi.org/10.1126/sciadv.aat2624

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