Tenectin recruits integrin to stabilize bouton architecture and regulate vesicle release at the Drosophila neuromuscular junction

Assembly, maintenance and function of synaptic junctions depend on extracellular matrix (ECM) proteins and their receptors. Here we report that Tenectin (Tnc), a Mucin-type protein with RGD motifs, is an ECM component required for the structural and functional integrity of synaptic specializations a...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Qi, Han, Tae Hee, Nguyen, Peter, Jarnik, Michal, Serpe, Mihaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040883/
https://www.ncbi.nlm.nih.gov/pubmed/29901439
http://dx.doi.org/10.7554/eLife.35518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040883/
https://www.ncbi.nlm.nih.gov/pubmed/29901439
http://dx.doi.org/10.7554/eLife.35518

Ejemplares similares