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Fork Protection and Therapy Resistance in Hereditary Breast Cancer

The BRCA-Fanconi anemia (FA) pathway preserves the genome and suppresses cancer and is a main determinant of chemotherapeutic efficacy. The hereditary breast cancer genes BRCA1 and BRCA2 function in DNA double-strand break repair mediating distinct steps of homologous recombination (HR). More recent...

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Detalles Bibliográficos
Autores principales: Cantor, Sharon B., Calvo, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041132/
https://www.ncbi.nlm.nih.gov/pubmed/29472318
http://dx.doi.org/10.1101/sqb.2017.82.034413