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AKT as a key target for growth promoting functions of neutral ceramidase in colon cancer cells

Despite advances in the field, colorectal cancer (CRC) remains a leading cause of cancer-related mortality worldwide. Research into bioactive sphingolipids over the past two decades has played an important role in increasing our understanding of the pathogenesis and therapeutics of CRC. In the compl...

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Detalles Bibliográficos
Autores principales: Coant, Nicolas, García-Barros, Mónica, Zhang, Qifeng, Obeid, Lina M., Hannun, Yusuf A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041258/
https://www.ncbi.nlm.nih.gov/pubmed/29662189
http://dx.doi.org/10.1038/s41388-018-0236-x