A TFEB nuclear export signal integrates amino acid supply and glucose availability

How cells coordinate the response to fluctuating carbon and nitrogen availability required to maintain effective homeostasis is a key issue. Amino acid limitation that inactivates mTORC1 promotes de-phosphorylation and nuclear translocation of Transcription Factor EB (TFEB), a key transcriptional re...

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Detalles Bibliográficos
Autores principales: Li, Linxin, Friedrichsen, Hans J., Andrews, Sarah, Picaud, Sarah, Volpon, Laurent, Ngeow, Kaochin, Berridge, Georgina, Fischer, Roman, Borden, Katherine L. B., Filippakopoulos, Panagis, Goding, Colin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041281/
https://www.ncbi.nlm.nih.gov/pubmed/29992949
http://dx.doi.org/10.1038/s41467-018-04849-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041281/
https://www.ncbi.nlm.nih.gov/pubmed/29992949
http://dx.doi.org/10.1038/s41467-018-04849-7

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