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Structural analyses of FERM domain-mediated membrane localization of FARP1

FARP1 is a multi-domain protein that is involved in regulating neuronal development through interacting with cell surface proteins such as class A Plexins and SynCAM 1. The N-terminal FERM domain in FARP1 is known to both promote membrane localization and mediate these protein interactions, for whic...

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Detalles Bibliográficos
Autores principales: Kuo, Yi-Chun, He, Xiaojing, Coleman, Andrew J., Chen, Yu-Ju, Dasari, Pranathi, Liou, Jen, Biederer, Thomas, Zhang, Xuewu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041286/
https://www.ncbi.nlm.nih.gov/pubmed/29992992
http://dx.doi.org/10.1038/s41598-018-28692-4