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DCE-MRI of Sunitinib-Induced Changes in Tumor Microvasculature and Hypoxia: A Study of Pancreatic Ductal Adenocarcinoma Xenografts()()

The purpose of this study was dual: to investigate (a) whether sunitinib may induce changes in tumor microvasculature and hypoxia in pancreatic ductal adenocarcinoma (PDAC) and (b) whether any changes can be detected by DCE-MRI. Sunitinib-treated and untreated control tumors of two PDAC xenograft mo...

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Detalles Bibliográficos
Autores principales: Wegner, Catherine S., Hauge, Anette, Simonsen, Trude G., Gaustad, Jon-Vidar, Andersen, Lise Mari K., Rofstad, Einar K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041378/
https://www.ncbi.nlm.nih.gov/pubmed/29886124
http://dx.doi.org/10.1016/j.neo.2018.05.006