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Contribution of Tau Pathology to Mitochondrial Impairment in Neurodegeneration

Tau is an essential protein that physiologically promotes the assembly and stabilization of microtubules, and participates in neuronal development, axonal transport, and neuronal polarity. However, in a number of neurodegenerative diseases, including Alzheimer’s disease (AD), tau undergoes pathologi...

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Detalles Bibliográficos
Autores principales: Pérez, María J., Jara, Claudia, Quintanilla, Rodrigo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041396/
https://www.ncbi.nlm.nih.gov/pubmed/30026680
http://dx.doi.org/10.3389/fnins.2018.00441