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Homozygous CREM-IbΔC-X Overexpressing Mice Are a Reliable and Effective Disease Model for Atrial Fibrillation

Background: Atrial fibrillation (AF) is a significant cause of morbidity and mortality with foreseeably increasing prevalence. While large animal models of the disease are well established but resource intensive, transgenic AF mouse models are not yet widely used to develop or validate novel therape...

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Detalles Bibliográficos
Autores principales: Stümpel, Frank T., Stein, Juliane, Himmler, Kirsten, Scholz, Beatrix, Seidl, Matthias D., Skryabin, Boris V., Müller, Frank U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041408/
https://www.ncbi.nlm.nih.gov/pubmed/30026696
http://dx.doi.org/10.3389/fphar.2018.00706