p53 Mediates Vast Gene Expression Changes That Contribute to Poor Chemotherapeutic Response in a Mouse Model of Breast Cancer()()

p53 is a transcription factor that regulates expression of genes involved in cell cycle arrest, senescence, and apoptosis. TP53 harbors mutations that inactivate its transcriptional activity in roughly 30% of breast cancers, and these tumors are much more likely to undergo a pathological complete re...

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Detalles Bibliográficos
Autores principales: Tonnessen-Murray, Crystal, Ungerleider, Nathan A., Rao, Sonia G., Wasylishen, Amanda R., Frey, Wesley D., Jackson, James G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041561/
https://www.ncbi.nlm.nih.gov/pubmed/29852458
http://dx.doi.org/10.1016/j.tranon.2018.05.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041561/
https://www.ncbi.nlm.nih.gov/pubmed/29852458
http://dx.doi.org/10.1016/j.tranon.2018.05.003

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