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Longevity of duodenal and peripheral T-cell and humoral responses to live-attenuated Salmonella Typhi strain Ty21a
BACKGROUND: We have previously demonstrated that polyfunctional Ty21a-responsive CD4(+) and CD8(+) T cells are generated at the duodenal mucosa 18 days following vaccination with live-attenuated S. Typhi (Ty21a). The longevity of cellular responses has been assessed in peripheral blood, but persiste...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041722/ https://www.ncbi.nlm.nih.gov/pubmed/29958737 http://dx.doi.org/10.1016/j.vaccine.2018.05.114 |