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Longevity of duodenal and peripheral T-cell and humoral responses to live-attenuated Salmonella Typhi strain Ty21a

BACKGROUND: We have previously demonstrated that polyfunctional Ty21a-responsive CD4(+) and CD8(+) T cells are generated at the duodenal mucosa 18 days following vaccination with live-attenuated S. Typhi (Ty21a). The longevity of cellular responses has been assessed in peripheral blood, but persiste...

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Detalles Bibliográficos
Autores principales:	Pennington, Shaun H., Ferreira, Daniela M., Reiné, Jesús, Nyirenda, Tonney S., Thompson, Ameeka L., Hancock, Carole A., Wright, Angela D., Gordon, Stephen B., Gordon, Melita A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Science 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041722/ https://www.ncbi.nlm.nih.gov/pubmed/29958737 http://dx.doi.org/10.1016/j.vaccine.2018.05.114

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